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Fasted cycling may change how immune cells burn fuel, study probes

NCT ID NCT07813403

Knowledge-focused Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

Researchers at Hacettepe University are studying how aerobic fitness and meal timing affect the body's use of fat and carbohydrates during exercise, and how immune cells called peripheral blood mononuclear cells (PBMCs) respond. Thirty healthy young men, split into high and low fitness groups, will cycle for 30 minutes at moderate intensity after an overnight fast. The high fitness group will also repeat the ride one hour after eating. The team will measure breathing gases during exercise and mitochondrial activity in blood samples taken before and after cycling.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acute moderate-intensity cycling exercise, performed after an overnight fast or one hour after a meal
What this could lead to
If the study finds links between fitness, meal timing, and how immune cells burn energy, it could shape future research on exercise, metabolism, and mitochondrial health.
What could go wrong
This is a small study of 30 healthy young men at one university, so its results may not apply to women, older adults, or people with health conditions. It measures short-term changes, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy male volunteers aged 18-25 years * Body mass index between 18.5 and 24.9 kg/m² * Residing on the Hacettepe University Beytepe Campus * Eligibility for one of the following aerobic fitness groups * High aerobic fitness group: maximal oxygen uptake (VO2max) greater than 55 mL/kg/min and regular participation in endurance training. * Low aerobic fitness group: VO2max lower than 45 mL/kg/min and sedentary or not regularly physically active Exclusion Criteria: * Current smoking * Regular or excessive alcohol consumption * Any musculoskeletal condition that may limit or prevent exercise * Allergy to any of the foods provided as part of the study meal * Currently following a weight-loss or other restrictive diet

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Conditions

The condition(s) this trial relates to.

inborn disorder of energy metabolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Energy metabolism Mitochondria Mitochondrial function, bioenergetics Physical fitness

How to take part

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  2. The official record

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Contacts and locations

Locations

  • Hacettepe University, Faculty of Sport Sciences

    Ankara, Ankara, 06800, Turkey (Türkiye)

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