Blood test may predict breast cancer return after chemo

NCT ID NCT06401421

Recruiting now Knowledge-focused Sponsor: Exact Sciences Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new blood test that looks for tiny bits of tumor DNA to see if it can predict whether high-risk early breast cancer will come back after chemotherapy. About 1,800 people with early-stage breast cancer who are about to start chemo will give blood and tissue samples. Researchers will follow them for up to 5.5 years to see if the test results match whether the cancer returns.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

AdventHealth East Altamonte Oncology and Hematology
RECRUITING

Altamonte Springs, Florida, 32701, United States
Alan B. Pearson Regional Cancer Center
RECRUITING

Lynchburg, Virginia, 24501, United States
Atrium Health Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Atrium Health Wake Forest Baptist Medical Center
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Aultman Timken Family Cancer Center
RECRUITING

Canton, Ohio, 44710, United States
Aurora Cancer Care - Wauwatosa
RECRUITING

Wauwatosa, Wisconsin, 53226, United States
Avera Cancer Institute
RECRUITING

Sioux Falls, South Dakota, 57105, United States
Ballad Health Cancer Center
RECRUITING

Kingsport, Tennessee, 37660, United States
Baptist Cancer Care - Plantation
RECRUITING

Plantation, Florida, 33324, United States
Baptist Health Louisville
RECRUITING

Louisville, Kentucky, 40207, United States
Bon Secours Cancer Institute at St. Francis
RECRUITING

Midlothian, Virginia, 23114, United States
Centre Hospitalier de l'Université de Montréal (CHUM)
RECRUITING

Montreal, Quebec, H2X 3E4, Canada
Cleveland Clinic Main Campus
RECRUITING

Cleveland, Ohio, 44195, United States
Deaconess Chancellor Center for Oncology
RECRUITING

Newburgh, Indiana, 47630, United States
FirstHealth Outpatient Cancer Center
RECRUITING

Pinehurst, North Carolina, 28374, United States
Greater Baltimore Medical Center
RECRUITING

Baltimore, Maryland, 21204, United States
Guthrie Sayre
RECRUITING

Sayre, Pennsylvania, 18840, United States
Harbor-UCLA Medical Center - Hematology / Oncology
RECRUITING

Torrance, California, 90502, United States
Holy Cross Hospital - Silver Spring
RECRUITING

Silver Spring, Maryland, 20910, United States
Hôpital du Saint-Sacrement
RECRUITING

Québec, Quebec, G1S 4L8, Canada
James M Stockman Cancer Institute
RECRUITING

Frederick, Maryland, 21702, United States
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T1E2, Canada
Joe Arrington Cancer Research & Treatment Center
RECRUITING

Lubbock, Texas, 79410, United States
John Theurer Cancer Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Kaiser Permanente Medical Center
RECRUITING

Vallejo, California, 94589, United States
Katmai Oncology Group - Anchorage
RECRUITING

Anchorage, Alaska, 99508, United States
Lahey Hospital & Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States
Maisonneuve-Rosemont Hospital (HMR)
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
McGill University Health - Glen Site
RECRUITING

Montreal, Quebec, Canada
MedStar Georgetown Cancer Institute
RECRUITING

Baltimore, Maryland, 21237, United States
Meritus Center for Clinical Research
RECRUITING

Hagerstown, Maryland, 21742, United States
Metro Minnesota Community Oncology Consortium (MMCORC)
RECRUITING

Saint Louis Park, Minnesota, 55426, United States
Mount Sinai Medical - Comprehensive Cancer Center
RECRUITING

Miami Beach, Florida, 33140, United States
Norton Cancer Institute - Downtown
RECRUITING

Louisville, Kentucky, 40202, United States
Novant Health Cancer Institute - Elizabeth
RECRUITING

Charlotte, North Carolina, 28204, United States
Penn State Cancer Institute
RECRUITING

Hershey, Pennsylvania, 17033, United States
Penn State Health Medical Group - Andrews Patel
RECRUITING

Harrisburg, Pennsylvania, 17111, United States
Rush Cancer Center
RECRUITING

Chicago, Illinois, 60607, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08901, United States
Saint Luke's Hospital of Kansas City
RECRUITING

Kansas City, Missouri, 64111, United States
Sinai Hospital of Baltimore
RECRUITING

Baltimore, Maryland, 21215, United States
Spartanburg Medical Center
RECRUITING

Spartanburg, South Carolina, 29303, United States
St. Elizabeth Edgewood Hospital
RECRUITING

Edgewood, Kentucky, 41017, United States
St. Joseph's Women's Hospital
RECRUITING

Tampa, Florida, 33607, United States
Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94304, United States
Stony Brook Medicine
RECRUITING

Stony Brook, New York, 11794, United States
Tate Cancer Center at UM Baltimore Washington
RECRUITING

Glen Burnie, Maryland, 21061, United States
The Center for Cancer and Blood Disorders - Bethesda
RECRUITING

Bethesda, Maryland, 20818, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
UCHealth Cancer Care - Anschutz Medical Campus - University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States
UNC Cancer Care at Nash
RECRUITING

Rocky Mount, North Carolina, 27804, United States
UPMC Magee - Womens Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States
University of Maryland St. Joseph Medical Center
RECRUITING

Towson, Maryland, 21204, United States
VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States
WVU Cancer Institute
RECRUITING

Morgantown, West Virginia, 26505, United States
Weinberg Center at Mercy
RECRUITING

Baltimore, Maryland, 21202, United States
Women & Infants Hospital
RECRUITING

Providence, Rhode Island, 02905, United States

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