New balloon could unclog heart stents without extra metal

NCT ID NCT05731700

Completed Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a special balloon coated with the drug everolimus in 51 people whose previously placed heart stents had become blocked again. The balloon is inflated inside the artery to deliver the drug directly to the blockage, aiming to keep the artery open. The main goals were to check safety and see how well the balloon prevented the artery from narrowing again.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: everolimus-coated balloon catheter
What this could lead to: If successful, this could offer a new way to reopen blocked stents without adding another permanent stent, reducing the need for repeat procedures.
What could go wrong: This is a small, early-stage study with no control group, so results may not hold up in larger trials. Risks include heart attack, blood clots, or the artery narrowing again.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary restenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IN-STENT RESTENOSIS

Contacts and locations

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Locations

Clinique Pasteur

Toulouse, 31300, France
Georgian Israeli Research Medical Centre Helsicore

Tbilisi, Georgia
Groupe Hospitalier Mutualiste de Grenoble

Grenoble, 38000, France
Hospital Clínic de Barcelona

Barcelona, 08036, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario de La Princesa

Madrid, 28006, Spain
L'Hôpital Privé du Confluent

Nantes, 44000, France
Tbilisi Heart and Vascular Clinic

Tbilisi, 0159, Georgia
Vilniaus universiteto ligoninė Santaros klinikos

Vilnius, 08410, Lithuania

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