New hope for tough schizophrenia cases? phase 3 trial launches

NCT ID NCT07184619

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 26 times

Summary

This study tests whether a new drug called evenamide can help people with treatment-resistant schizophrenia whose symptoms are not well controlled by their current antipsychotic medication. About 400 adults will receive either evenamide or a placebo added to their usual treatment for 12 weeks. The goal is to see if evenamide reduces symptoms like hallucinations and delusions more than placebo, and to check its safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grady Behavioral Health Center, -Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Manhattan Psychiatric Center, The Nathan Kline Institute for Psychiatric Research

    RECRUITING

    New York, New York, 10035, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA DGSOM, UCLA Health, UCLA Semel Institute

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami, Miller School of Medicine; Jackson Behavioral Health Hospital

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.