New hope for Treatment-Resistant schizophrenia? phase 3 trial launches

NCT ID NCT07184619

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called evenamide for people with schizophrenia that hasn't improved with standard antipsychotics. About 400 adults will receive either evenamide or a placebo added to their current medication for 12 weeks. The goal is to see if evenamide reduces symptoms like hallucinations and delusions better than placebo, and to check its safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Schizophrenia Schizophrenia, Treatment-Resistant treatment-refractory schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ahana Hospitals LLP

    RECRUITING

    Madurai, Tamil Nadu, 625020, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine

    SUSPENDED

    Baltimore, Maryland, 21224, United States

  • Grady Behavioral Health Center, -Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine

    SUSPENDED

    Atlanta, Georgia, 30322, United States

  • Help Hospital

    NOT_YET_RECRUITING

    Vijayawada, Andhra Pradesh, 520002, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Manhattan Psychiatric Center, The Nathan Kline Institute for Psychiatric Research

    SUSPENDED

    New York, New York, 10035, United States

  • Masina Hospital Trust

    RECRUITING

    Mumbai, Maharashtra, 400027, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seth Sukhlal Karnani Memorial Hospital

    NOT_YET_RECRUITING

    Kolkata, West Bengal, 700025, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA DGSOM, UCLA Health, UCLA Semel Institute

    SUSPENDED

    Los Angeles, California, 90095, United States

  • Udyan Health Care

    RECRUITING

    Lucknow, Uttar Pradesh, 226012, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami, Miller School of Medicine; Jackson Behavioral Health Hospital

    SUSPENDED

    Miami, Florida, 33136, United States