New Needle-Free treatment could replace surgery for adrenal tumors

NCT ID NCT05368090

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new, less invasive procedure called EUS-RFA to standard surgery for treating left-sided adrenal tumors that cause high blood pressure and other hormone-related issues. About 60 participants will receive the new procedure, which uses a thin tube inserted through the mouth to deliver heat and destroy the tumor. Researchers will check if it controls hormone levels as well as surgery, with fewer side effects and a shorter hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation (RFA) delivered via endoscopic ultrasound

What this could lead to

If successful, this could offer a less invasive alternative to surgery for controlling hormone overproduction in primary aldosteronism, reducing recovery time and complications.

What could go wrong

This is an early-stage study with only 60 participants, so results may not apply broadly. The procedure carries risks like bleeding or infection, and it may not control hormone levels as effectively as surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma aldosterone-producing adrenal cortex adenoma Cushing syndrome hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Haukeland University Hospital

    RECRUITING

    Bergen, 5021, Norway

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••