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New Needle-Free treatment could replace surgery for adrenal tumors

NCT ID NCT05368090

Recruiting now Disease control Sponsor: Haukeland University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new, less invasive procedure called EUS-RFA to standard surgery for treating left-sided adrenal tumors that cause high blood pressure and other hormone-related issues. About 60 participants will receive the new procedure, which uses a thin tube inserted through the mouth to deliver heat and destroy the tumor. Researchers will check if it controls hormone levels as well as surgery, with fewer side effects and a shorter hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiofrequency ablation (RFA) delivered via endoscopic ultrasound
What this could lead to
If successful, this could offer a less invasive alternative to surgery for controlling hormone overproduction in primary aldosteronism, reducing recovery time and complications.
What could go wrong
This is an early-stage study with only 60 participants, so results may not apply broadly. The procedure carries risks like bleeding or infection, and it may not control hormone levels as effectively as surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma aldosterone-producing adrenal cortex adenoma Cushing syndrome hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALDOSTERONE-PRODUCING ADENOMA HYPERCORTISOLISM PRIMARY ALDOSTERONISM

Contacts and locations

Locations

  • Haukeland University Hospital

    RECRUITING

    Bergen, 5021, Norway

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