Nasal spray may offer quick fix for Children's racing heart

NCT ID NCT05763953

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether etripamil nasal spray can safely and quickly stop episodes of paroxysmal supraventricular tachycardia (PSVT) in children aged 6 to 17. PSVT causes sudden rapid heartbeats that can be frightening and require medical attention. The spray is designed to be used at the onset of symptoms, potentially avoiding emergency room visits. The trial will evaluate how well the spray restores normal heart rhythm within 15 minutes and monitor for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
etripamil nasal spray
What this could lead to
If successful, this could provide a fast, needle-free way for children to stop PSVT episodes at home, reducing emergency visits.
What could go wrong
This is an early-phase study with a small number of children, so results may not confirm safety or effectiveness. Side effects from the nasal spray are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advocate Children's Hospital

    NOT_YET_RECRUITING

    Oak Lawn, Illinois, 60453, United States

    Contact Email: •••••@•••••

    Contact

  • Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital Medical Center

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Email: •••••@•••••

    Contact

  • Hospital Infantil Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

    Contact

    Contact

  • Hospital Sant Joan de Déu

    NOT_YET_RECRUITING

    Barcelona, 08950, Spain

    Contact

    Contact

  • Le Bonheur Children's Hospital

    NOT_YET_RECRUITING

    Memphis, Tennessee, 38103, United States

    Contact Email: •••••@•••••

    Contact

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact

  • Phoenix Children's Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact Email: •••••@•••••

    Contact

  • The University of British Columbia

    NOT_YET_RECRUITING

    Vancouver, V6H3V4, Canada

    Contact

    Contact

  • Universitätsmedizin Göttingen, Klinik für Pädiatrische Kardiologie, Intensivmedizin und Neonatologie

    NOT_YET_RECRUITING

    Göttingen, 37075, Germany

    Contact

    Contact

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