Can a tailored Stop-Smoking program help cancer patients quit?
NCT ID NCT04694846
First seen Jun 26, 2026 ยท Last updated Jun 26, 2026
Summary
This study tested an enhanced tobacco intervention program (ETIP) for people with head and neck or lung cancer who smoke. The program combined counseling, nicotine replacement, and medications like bupropion or varenicline. Nineteen participants were enrolled to see if the program could reduce smoking by at least half. The goal was to help patients quit smoking to potentially improve their cancer treatment outcomes.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Nicotine replacement therapy, bupropion, and varenicline
- What this could lead to
- If successful, this approach could help cancer patients quit smoking, potentially improving treatment outcomes and reducing cancer progression.
- What could go wrong
- This was a small feasibility study with only 19 participants, so results may not apply broadly. The intervention may not lead to long-term abstinence or affect tumor biology.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Jefferson Health, Methodist Hospital
Philadelphia, Pennsylvania, 19148, United States
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Sidney Kimmel Cancer Center at Thomas Jefferson Univeristy
Philadelphia, Pennsylvania, 19107, United States
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