New inhaled drug shows promise for cystic fibrosis in early trial

NCT ID NCT06478706

Completed Disease control Sponsor: Enterprise Therapeutics Ltd Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an inhaled drug called ETD001 in 57 adults with cystic fibrosis. The trial had two parts: one to check safety over 7 days, and another to see if the drug improves lung function over 28 days. Participants took the drug or a placebo twice daily. The goal is to find a new treatment that helps people with CF breathe easier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ETD001 (inhaled drug)
What this could lead to: If successful, this could lead to a new inhaled treatment that improves lung function in people with cystic fibrosis.
What could go wrong: This is an early Phase 2 trial with only 57 participants, so results may not apply to everyone. The drug may not improve lung function or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS

Contacts and locations

Locations

All Wales Adult CF Centre

Cardiff, CF64 2XX, United Kingdom
Azienda Ospedaliera Universitaria Integrata Verona

Verona, 37126, Italy
Azienda Ospedaliera Universitaria Meyer

Florence, 50139, Italy
Belfast Health and Social Care Trust

Belfast, BT9 7AB, United Kingdom
CF-Studienzentrum Universitätsklinikum Köln

Cologne, 50924, Germany
CHU de Montpellier

Montpellier, 34295, France
Charité Universtaetsmedizin

Berlin, 13353, Germany
Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Milan, 20122, Italy
Hospices Civils de Lyon

Lyon, 69495, France
Hôpital Cochin

Paris, 75014, France
Hôpitaux de Toulouse

Toulouse, 31059, France
IKF Pneumologie

Frankfurt, 60596, Germany
IRCCS Istituto Giannina Gaslini

Genova, 16147, Italy
LMU Kinikum

Munich, 80336, Germany
Ospedale Pediatrico Bambino Gesù

Roma, 00165, Italy
Queen Elizabeth University Hospital West of Scotland CF Service

Glasgow, G51 4TR, United Kingdom
Royal Brompton Hospital

London, SW3 6LL, United Kingdom
Royal Papworth Hospital

Cambridge, CB2 0AY, United Kingdom
Southampton General Hospital

Southampton, SO16 6YD, United Kingdom
Universitätsklinikum Frankfurt

Frankfurt, 60590, Germany
Westdeutsches Lungenzentrum am Universitätsklinikum

Essen, 45239, Germany

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