New daily pill could ease sickle cell pain for kids

NCT ID NCT06198712

Recruiting now Disease control Sponsor: Forma Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study tests a once-daily pill called etavopivat in children (6 months to 18 years) with sickle cell disease. The main goals are to check safety and how the drug works in the body, and to see if it can raise hemoglobin levels and reduce painful crises. About 95 children will take the pill every day for 96 weeks, with follow-up visits to track results.

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Conditions

The condition(s) this trial relates to.

sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SICKLE CELL DISEASE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

APHP - Centre de Référence des Syndromes
NOT_YET_RECRUITING

Paris, 75019, France
Acıbadem Adana Hastanesi
COMPLETED

Seyhan, 1130, Turkey (Türkiye)
Ahero Clinical Trials Unit
RECRUITING

Kisumu, 40101, Kenya
American University of Beirut Medical center
RECRUITING

Beirut, 1107 2020, Lebanon
Aminu Kano Teaching Hospital (AKTH)
RECRUITING

Tarauni, 700101, Nigeria
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle
NOT_YET_RECRUITING

Roeun, 76031, France
Guys and St Thomas NHS Foundation Trust / Evelina Childrens Hospital
RECRUITING

London, SE1 7EH, United Kingdom
HCL-HOPITAL LYON SUD_Institut d'Hématologie et d'Oncologie Pédiatrique (IHOPe)
NOT_YET_RECRUITING

Lyon, 69008, France
Hacettepe University pediatric hematology
COMPLETED

Ankara, 06100, Turkey (Türkiye)
Hospital Nini
RECRUITING

Tripoli, 113-6044, Lebanon
KEMRI CRDR Siaya Clinical Research Annex, Country Referral Hospital
NOT_YET_RECRUITING

Siaya, Siaya County, 40600, Kenya
KEMRI-Walter-Reed Kericho
NOT_YET_RECRUITING

Kericho, 20200, Kenya
King's College Hospital - Alex Mowat Research Hub
RECRUITING

London, SE5 9RS, United Kingdom
Kombewa Clinical Research Centre
NOT_YET_RECRUITING

Kisumu, 40100, Kenya
Lagos University Teaching Hospital, Lagos
RECRUITING

Lagos, 102215, Nigeria
Manchester Royal Infirmary_1
RECRUITING

Manchester, M13 9WL, United Kingdom
The Hospital for Sick Children
COMPLETED

Toronto, Ontario, M5G 1X8, Canada
University of Nigeria Teaching Hospital (UNTH)
RECRUITING

Ituku-Ozalla, Enugu State, 400001, Nigeria

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