New sickle cell drug put to the test: will it clash with your other meds?

This study looked at whether a new medicine called etavopivat (for sickle cell disease and thalassemia) changes how the body processes five common drugs: digoxin, rosuvastatin, midazolam, pitavastatin, and metformin. Thirty-seven healthy adults took etavopivat daily for 10 days along with single doses of these other medicines. Researchers measured drug levels in the blood to see if etavopivat affected their breakdown. The goal was to gather safety information for future patients who might need both treatments.