New sickle cell drug put through drug interaction test in healthy volunteers

This study tested whether a new medicine called etavopivat changes how the body processes five common drugs: digoxin, rosuvastatin, pitavastatin, metformin, and midazolam. Thirty-seven healthy adults took etavopivat daily for 10 days along with single doses of each common drug. The goal was to see if etavopivat affects the levels of these drugs in the blood, which helps doctors know if dose adjustments are needed when prescribing them together.