New hope for stubborn high blood pressure: drug targets blood vessels

NCT ID NCT04388124

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with resistant hypertension, meaning their blood pressure stays high even with three or more medications. Researchers want to see if a drug that blocks endothelin-1, a substance that tightens blood vessels, can improve blood vessel function and lower blood pressure over 8 weeks. About 24 adults aged 30-80 will take part. The goal is to find a better way to control this serious condition and reduce heart risks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chu Rouen

    RECRUITING

    Rouen, 76031, France

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