Sleep apnea treatment may boost brain health in seniors

NCT ID NCT05988385

First seen Nov 11, 2025 · Last updated May 24, 2026 · Updated 25 times

Summary

This study looks at whether successfully treating obstructive sleep apnea (OSA) in older adults can improve memory and lower Alzheimer's-related brain changes. About 200 cognitively normal adults aged 55-85 with moderate-to-severe OSA will either receive immediate treatment (CPAP, oral appliance, or positional therapy) or join a waitlist. Researchers will track memory, thinking skills, and blood markers of Alzheimer's over two years to see if better sleep leads to better brain health.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai

    RECRUITING

    New York, New York, 10023, United States

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  • New York University

    RECRUITING

    New York, New York, 10016, United States

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    Contact

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85719, United States

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  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

Conditions

Explore the condition pages connected to this study.