Could a single dose of esketamine soothe IBS?

NCT ID NCT06788444

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study is testing whether a single low dose of esketamine can reduce symptoms of irritable bowel syndrome (IBS) in 552 adults aged 18-60 who also have anxiety or depression. Participants will receive the drug during a colonoscopy, and their IBS severity and quality of life will be checked 6 weeks later. The goal is to see if this approach provides meaningful symptom relief.

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Contacts and locations

Locations

  • Beijing Tiantan Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100050, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.