Could a nasal spray boost PTSD therapy? small study says maybe

NCT ID NCT06795659

First seen Jan 29, 2026 · Last updated May 14, 2026 · Updated 15 times

Summary

This early study tested whether adding esketamine (a nasal spray used for depression) to a proven talk therapy called Prolonged Exposure could help people with PTSD feel better. Only 4 adults took part, and the main goal was to see if the combination was practical and well-liked. The results suggest the approach is worth studying further, but it's too early to know if it truly improves PTSD symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.