New patch could ease ankle sprain pain without pills

NCT ID NCT06866613

Completed Symptom relief Sponsor: Teikoku Seiyaku Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a medicated patch containing esflurbiprofen, a pain-relieving drug, against a placebo patch in 69 adults with mild ankle sprains. Participants wore the patch for 7 days. The goal was to see if the patch reduces pain during movement better than a placebo. The trial is already completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: esflurbiprofen topical patch
What this could lead to: If it works, this could provide a convenient, non-oral pain relief option for ankle sprains.
What could go wrong: This is a small, completed Phase 3 trial with only 69 participants. Results may not apply to all sprains or other injuries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ankle injury Athletic Injuries Soft Tissue Injuries Wounds, Nonpenetrating

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKLE SPRAINS

Contacts and locations

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Locations

Medical Practice Ebert

Siemensstr, Bonn, 53121, Germany
Medical Practice Gastl

Römerstraße, Gilching, 82205, Germany
Medical Practice Pabst

Sportschule Puch, Fürstenfeldbruck, 82556, Germany
Medical Practice Prof. Predel

Siemensstr, Bonn, 53121, Germany
Medical Practice Schaale-Maas

Siemensstr, Bonn, 53121, Germany

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