Drug cocktail aims to stall pancreatic cancer in patients who have run out of options

NCT ID NCT00640978

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether combining two drugs—erlotinib and everolimus—can slow the growth of advanced pancreatic cancer in patients who have already received at least one prior treatment. The study enrolls people with unresectable or metastatic pancreatic adenocarcinoma and measures how many survive at 6 months, as well as how long the cancer stays under control. Researchers are also monitoring safety and side effects of the combination.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
erlotinib and everolimus
What this could lead to
If successful, this drug combination could offer a new treatment option to slow advanced pancreatic cancer in patients who have already tried other therapies.
What could go wrong
This is an early-phase trial with only 16 participants, so results may not apply broadly. The combination may cause side effects and might not improve survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • U.T.M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

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