New drug targets rare gene mutations in Hard-to-Treat cancers

NCT ID NCT06351371

First seen Oct 31, 2025 · Last updated Jun 14, 2026 · Updated 37 times

Summary

This study tests a pill called erdafitinib in 35 adults whose cancers have specific FGFR gene mutations or fusions. The drug blocks a faulty protein that helps cancer grow, potentially shrinking tumors or slowing the disease. It is a phase 2 trial for advanced solid tumors that have not responded to other treatments.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.