Could an epinephrine shot prevent pancreatitis after ERCP?
NCT ID NCT07173179
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether injecting epinephrine around the bile duct opening, combined with a standard rectal anti-inflammatory drug, could reduce pancreatitis after ERCP—a common procedure to treat bile duct blockages. Over 500 adults with a first-time ERCP took part. The goal was to see if the combination worked better than the anti-inflammatory drug alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
epinephrine injection and rectal indomethacin
What this could lead to
If it works, this could offer a simple, low-cost way to lower the risk of pancreatitis after a common bile duct procedure.
What could go wrong
This is a completed Phase 4 trial, but the results are not yet published. The added benefit of epinephrine injection over standard care may be small, and injection carries a slight risk of bleeding or tissue damage.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duzce University School of Medicine
Düzce, 81620, Turkey (Türkiye)