New hope for down syndrome vision loss: corneal crosslinking trial launches

NCT ID NCT07135167

First seen Feb 02, 2026 · Last updated May 13, 2026 · Updated 13 times

Summary

This study tests an experimental eye treatment called corneal crosslinking (CXL) for people with Down syndrome who have a condition that makes the front of the eye thin and misshapen, causing blurry vision. The treatment uses vitamin B2 drops and ultraviolet light to strengthen the cornea and stop vision from getting worse. The study will enroll 225 participants aged 8 and older and follow them for 6 months to see if the treatment slows disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Woolfson Eye Institute

    RECRUITING

    Atlanta, Georgia, 30328, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Atlanta, Georgia, 30349, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Canton, Georgia, 30114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Cumming, Georgia, 30041, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Douglasville, Georgia, 30134, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Lawrenceville, Georgia, 30043, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Marietta, Georgia, 30066, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Snellville, Georgia, 30078, United States

    Contact Phone: •••-•••-••••

  • Woolfson Eye Institute

    RECRUITING

    Asheville, North Carolina, 28803, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Chattanooga, Tennessee, 37421, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woolfson Eye Institute

    RECRUITING

    Johnson City, Tennessee, 37615, United States

    Contact Phone: •••-•••-••••

  • Woolfson Eye Institute

    RECRUITING

    Knoxville, Tennessee, 37922, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.