New vaccine combo shows promise for Hard-to-Treat cancers

NCT ID NCT05631899

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This early-phase trial tests a custom-made vaccine using a patient's own immune cells, designed to target specific cancer markers (EphA2 and KRAS mutations). The vaccine is given together with two immunotherapy drugs to boost the immune system's attack on tumors. The study includes up to 9 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and see if the combination can shrink tumors or control the disease.

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Contacts and locations

Locations

  • Biotherapeutic Department of Chinsese PLA Gereral Hospital

    Beijing, Beijing Municipality, 100853, China

Conditions

Explore the condition pages connected to this study.