Hidden blood vessel damage may predict heart surgery complications

NCT ID NCT02965339

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether patients with pre-existing endothelial dysfunction (damage to the inner lining of blood vessels) are more likely to develop vasoplegia (a dangerous drop in blood pressure) after cardiac surgery using a heart-lung machine. Researchers will measure various markers of endothelial function in adults undergoing coronary artery bypass or aortic valve surgery. The goal is to understand if pre-existing vessel damage contributes to post-surgery complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If a link is found, it could help identify patients at higher risk for complications after heart surgery, allowing for closer monitoring or preventive measures.

What could go wrong

This is an observational study, so it cannot prove cause and effect. The results may not lead to changes in care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

palsy Vasoplegia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU De Caen

    Caen, Caen, 14000, France