Scarless surgery? endoscopic mastectomy may keep nipple sensation intact

NCT ID NCT07718425

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study tests a minimally invasive technique called endoscopic nipple-sparing mastectomy for women with breast cancer or high genetic risk. Surgeons remove breast tissue through a small side incision using a camera, then reconstruct the breast immediately with an implant. The goal is to see if this approach reduces scarring and recovery time while preserving nipple sensation and cosmetic outcomes. Thirty women will be followed for up to 5 years to assess safety, sensation recovery, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
endoscopic nipple-sparing mastectomy (a minimally invasive surgical procedure)
What this could lead to
If successful, this approach could offer a less invasive mastectomy option with better cosmetic results and preserved nipple sensation.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply broadly. Surgical risks include infection, necrosis, and implant loss.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ospedale degli Infermi ASL BI

    RECRUITING

    Ponderano, BI, 13875, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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