New study aims to spare thousands of breast cancer patients from unnecessary chemo

NCT ID NCT07379918

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at a genomic test called EndoPredict that analyzes tumor genes to predict the risk of breast cancer returning. The goal is to see if women with a low-risk score can safely skip chemotherapy and only take hormone therapy. Researchers will follow 1,000 patients for 10 years to track relapse and survival rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EndoPredict genomic test

What this could lead to

If successful, this could help doctors safely skip chemotherapy for many women with early breast cancer, reducing side effects without increasing relapse risk.

What could go wrong

This is an observational study, not a treatment trial. It will gather real-world data but won't directly prove that skipping chemotherapy is safe for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Her2-receptor negative breast cancer hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Saint-Louis

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••