Could ring fit adventures fight depression in breast cancer survivors?
NCT ID NCT07721753
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether combining a video game exercise program (Nintendo Ring Fit Adventure) with Acceptance and Commitment Therapy (ACT) can reduce depression and anxiety in breast cancer survivors. About 120 participants will be randomly assigned to the combined program, ACT alone, or usual care. Researchers will measure changes in mood, quality of life, and certain blood markers over 20 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a program combining exergames (Nintendo Ring Fit Adventure) with Acceptance and Commitment Therapy (ACT)
- What this could lead to
- If it works, this could offer a new, engaging way to improve mental health and quality of life for breast cancer survivors.
- What could go wrong
- This is a relatively small, early-stage trial. The added benefit of exergames over ACT alone is unproven, and results may not apply to all survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
The inclusion criteria include: 1. Newly diagnosed breast cancer patients and patients with recurrent breast cancer confirmed by histopathological report, regardless of the stage of cancer. 2. Those with HADS score of 8 or higher in both Depression and Anxiety sub-scales of the HADS. 3. Patients who had been treated with surgery or were undergoing the standard regime of clinical anti-tumor treatment (chemotherapy, radiotherapy, immunotherapy, targeted therapy, etc.). 4. Age 18 years old and above. 5. Patients who were able to read and understand written Chinese. The exclusion criteria are: 1. Pregnant women,considered for the following reasons: Pregnancy involves significant hormonal and physical changes that could affect the participant's response to the e-ACT; the safety of e-ACT to the unborn child was of concern. 2. Those who have current and lifetime history of engaging in any psychotherapy 3. Those who consumed alcohol and illicit drugs . 4. Those who has current and lifetime history of other psychiatric illnesses, such as psychotic disorders (schizophrenia, schizophreniform disorder, schizoaffective disorders, brief psychotic disorder, and delusional disorder), bipolar mood disorder, obsessive compulsive disorder, posttraumatic stress disorder, and attention deficit hyperactive disorder, and autism spectrum disorder 5. Those who are on medications that can induce psychiatric symptoms, such as cardiovascular agents (clonidine, guanethidine, methyldopa, reserpine, beta blockers), dermatologic agents (isotretinoin), anticonvulsants (levetiracetam), antimigraine medications (triptans), hormonal agents (corticosteroids, oral contraceptives, gonadotropin-releasing hormone agonists, tamoxifen), varenicline, immunological agents (interferons), and levodopa.Or those who ccurrently using any psychotropic medication. 6. Patient who has suicidal tendency. 7. those who are physically unfit to answer questionnaires. (those are bed-bound or too weak to answer the questionnaire).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of Henan Medical University
RECRUITINGXinxiang, Henan, 453100, China
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