New hope for hard-to-treat endometrial cancer: combo therapy trial underway

NCT ID NCT04486352

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tests whether combining targeted drugs with the immunotherapy atezolizumab can shrink tumors or slow cancer growth in people with recurrent or persistent endometrial cancer. About 148 participants whose cancer has returned after at least one prior treatment will receive treatments matched to their tumor's genetic markers. The goal is to improve response rates and delay progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atlantic Health Systems/Morristown Medical Center

    ACTIVE_NOT_RECRUITING

    Morristown, New Jersey, 07960, United States

  • Baptist Memorial Hospital

    WITHDRAWN

    Memphis, Tennessee, 38120, United States

  • City of Hope Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02125, United States

  • Duke University Cancer Center

    ACTIVE_NOT_RECRUITING

    Durham, North Carolina, 27710, United States

  • Englewood Health

    ACTIVE_NOT_RECRUITING

    Englewood, New Jersey, 07631, United States

  • Lifespan - Rhode Island Hospital

    ACTIVE_NOT_RECRUITING

    Providence, Rhode Island, 02903, United States

  • Maine Medical Center

    ACTIVE_NOT_RECRUITING

    Scarborough, Maine, 04074, United States

  • Medstar Georgetown Cancer Institute

    ACTIVE_NOT_RECRUITING

    Washington D.C., District of Columbia, 20007, United States

  • Mount Sinai Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    Miami Beach, Florida, 33140, United States

  • Nebraska Methodist Hospital

    ACTIVE_NOT_RECRUITING

    Omaha, Nebraska, 68114, United States

  • Providence Portland Cancer Institute

    ACTIVE_NOT_RECRUITING

    Portland, Oregon, 97213, United States

  • Roswell Park

    ACTIVE_NOT_RECRUITING

    Buffalo, New York, 14263, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94143, United States

  • University of Chicago

    ACTIVE_NOT_RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Kansas Cancer Center

    ACTIVE_NOT_RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Minnesota

    ACTIVE_NOT_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Oklahoma Health Stephenson Cancer Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact

    Contact

  • University of Pittsburgh Medical Center

    ACTIVE_NOT_RECRUITING

    Pittsburgh, Pennsylvania, 15261, United States

  • Washington University School of Medicine Siteman Cancer Center

    WITHDRAWN

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medicine

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.