Could less surgery be better for endometrial cancer?

NCT ID NCT02658565

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether doctors can safely remove fewer lymph nodes during surgery for endometrial cancer by using a quick lab test during the operation. The goal is to reduce side effects like pain and swelling while still catching cancer that has spread. About 400 women with endometrial cancer will take part, and researchers will track how well they do over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Lymphadenectomy (surgical removal of lymph nodes)
What this could lead to
If successful, this could show that a tailored surgical approach is safe and effective, potentially reducing unnecessary lymph node removal and its side effects for many women.
What could go wrong
This is an observational validation study, not a randomized trial, so results may not prove cause and effect. The approach may not work for all patients or could miss cancer spread.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

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