Three-Way drug fight against advanced uterine cancer

NCT ID NCT00977574

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study aims to find the most effective drug combination for controlling advanced or recurrent endometrial cancer. It enrolled 349 patients to test three different mixes of chemotherapy and targeted therapy drugs. The goal is to see which combination best slows cancer growth and extends life for patients with this serious condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AdventHealth Orlando

Orlando, Florida, 32803, United States
Advocate Sherman Hospital

Elgin, Illinois, 60123, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Ascension Saint Vincent Indianapolis Hospital

Indianapolis, Indiana, 46260, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Beacon Kalamazoo

Kalamazoo, Michigan, 49048, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States
Cancer Center of Kansas - McPherson

McPherson, Kansas, 67460, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Liberal

Liberal, Kansas, 67905, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Research for the Ozarks NCORP

Springfield, Missouri, 65804, United States
Carilion Roanoke Memorial Hospital

Roanoke, Virginia, 24033, United States
Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Center of Hope at Renown Medical Center

Reno, Nevada, 89502, United States
Central Georgia Gynecologic Oncology

Macon, Georgia, 31201, United States
Christiana Care - Union Hospital

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Clements University Hospital

Dallas, Texas, 75390, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Community Howard Regional Health

Kokomo, Indiana, 46904, United States
Cone Health Cancer Center at Alamance Regional

Burlington, North Carolina, 27215, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States
Corewell Health Lakeland Hospitals - Niles Hospital

Niles, Michigan, 49120, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085, United States
Corewell Health William Beaumont University Hospital

Royal Oak, Michigan, 48073, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Elkhart Clinic

Elkhart, Indiana, 46514-2098, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesys Regional Medical Center-West Flint Campus

Flint, Michigan, 48532, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Henry Ford Health Warren Hospital

Warren, Michigan, 48093, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Hinsdale Hematology Oncology Associates Incorporated

Hinsdale, Illinois, 60521, United States
Hope Women's Cancer Centers-Asheville

Asheville, North Carolina, 28816, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
IU Health La Porte Hospital

La Porte, Indiana, 46350, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Iowa-Wide Oncology Research Coalition NCORP

Des Moines, Iowa, 50309, United States
Island Gynecologic Oncology

Brightwaters, New York, 11718, United States
Jefferson Abington Hospital

Abington, Pennsylvania, 19001, United States
John Muir Medical Center-Concord

Concord, California, 94520, United States
John Muir Medical Center-Walnut Creek

Walnut Creek, California, 94598, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Lake Huron Medical Center

Port Huron, Michigan, 48060, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103, United States
Lyndon Baines Johnson General Hospital

Houston, Texas, 77026-1967, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MU Health - University Hospital/Ellis Fischel Cancer Center

Columbia, Missouri, 65212, United States
MaineHealth Maine Medical Center - Portland

Portland, Maine, 04102, United States
Maui Memorial Medical Center

Wailuku, Hawaii, 96793, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Baltimore, Maryland, 21237, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Health University Medical Center

Savannah, Georgia, 31404, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Mercy Cancer Center-West Lakes

Clive, Iowa, 50325, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy Medical Center-West Lakes

West Des Moines, Iowa, 50266, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Michiana Hematology Oncology PC-Elkhart

Elkhart, Indiana, 46514, United States
Michiana Hematology Oncology PC-Mishawaka

Mishawaka, Indiana, 46545, United States
Michiana Hematology Oncology PC-Plymouth

Plymouth, Indiana, 46563, United States
Michiana Hematology Oncology PC-Westville

Westville, Indiana, 46391, United States
Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States
Morristown Medical Center

Morristown, New Jersey, 07960, United States
Morton Plant Hospital

Clearwater, Florida, 33756, United States
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

Spokane, Washington, 99204, United States
MultiCare Tacoma General Hospital

Tacoma, Washington, 98405, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
New York Hospital Medical Center of Queens

Fresh Meadows, New York, 11365, United States
Northern Indiana Cancer Research Consortium

South Bend, Indiana, 46628, United States
Northwestern University

Chicago, Illinois, 60611, United States
Novant Health Presbyterian Medical Center

Charlotte, North Carolina, 28204, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa

Tulsa, Oklahoma, 74146, United States
Olympic Medical Cancer Care Center

Sequim, Washington, 98384, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States
Overlook Hospital

Summit, New Jersey, 07902, United States
Pacific Cancer Institute of Maui

Wailuku, Hawaii, 96793, United States
Pacific Gynecology Specialists

Seattle, Washington, 98104, United States
Pali Momi Medical Center

‘Aiea, Hawaii, 96701, United States
Palo Alto Medical Foundation-Gynecologic Oncology

Mountain View, California, 94040, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
PeaceHealth Medical Group PC

Bellingham, Washington, 98226, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Pennsylvania Hospital

Philadelphia, Pennsylvania, 19107, United States
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Providence Regional Cancer Partnership

Everett, Washington, 98201, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362, United States
Queen's Cancer Center - Kuakini

Honolulu, Hawaii, 96817, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Renown Regional Medical Center

Reno, Nevada, 89502, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Rocky Mountain Gynecologic Oncology PC

Englewood, Colorado, 80110, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rush MD Anderson Cancer Center

Chicago, Illinois, 60612, United States
Rutgers New Jersey Medical School

Newark, New Jersey, 07101, United States
SSM Health Saint Louis University Hospital

St Louis, Missouri, 63104, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Dominic-Jackson Memorial Hospital

Jackson, Mississippi, 39216, United States
Saint Joseph Medical Center

Tacoma, Washington, 98405, United States
Saint Joseph Regional Medical Center-Mishawaka

Mishawaka, Indiana, 46545, United States
Saint Joseph's Hospital and Medical Center

Phoenix, Arizona, 85013, United States
Saint Luke's Hospital-Warren Campus

Phillipsburg, New Jersey, 08865, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
San Diego VA Medical Center

San Diego, California, 92161, United States
Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Scott and White Memorial Hospital

Temple, Texas, 76508, United States
Sinai Hospital of Baltimore

Baltimore, Maryland, 21215, United States
Singing River Hospital

Pascagoula, Mississippi, 39581, United States
Skagit Regional Health Cancer Care Center

Mount Vernon, Washington, 98274, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
South Bend Clinic

South Bend, Indiana, 46617, United States
South Carolina Oncology Associates PA

Columbia, South Carolina, 29210, United States
Southwest Gynecologic Oncology Associates Inc

Albuquerque, New Mexico, 87106, United States
State University of New York Downstate Medical Center

Brooklyn, New York, 11203, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Straub Clinic and Hospital

Honolulu, Hawaii, 96813, United States
Sudarshan K Sharma MD Limited-Gynecologic Oncology

Hinsdale, Illinois, 60521, United States
Summa Health System - Akron Campus

Akron, Ohio, 44304, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
UC San Diego Medical Center - Hillcrest

San Diego, California, 92103, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, 90095, United States
UCSF Medical Center-Mount Zion

San Francisco, California, 94115, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
UMass Memorial Medical Center - Memorial Division

Worcester, Massachusetts, 01605, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Hawaii Cancer Center

Honolulu, Hawaii, 96813, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Virginia Cancer Center

Charlottesville, Virginia, 22908, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
University of Washington Medical Center - Northwest

Seattle, Washington, 98133, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Virginia Oncology Associates - Norfolk

Norfolk, Virginia, 23502, United States
Virginia Oncology Associates-Hampton

Hampton, Virginia, 23666, United States
Virtua Memorial

Mount Holly, New Jersey, 08060, United States
Virtua Voorhees

Voorhees Township, New Jersey, 08043, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wenatchee Valley Hospital and Clinics

Wenatchee, Washington, 98801, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States
Wilcox Memorial Hospital and Kauai Medical Clinic

Lihue, Hawaii, 96766, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States
Women's Cancer Care Associates LLC

Albany, New York, 12208, United States
Women's Cancer Center of Nevada

Las Vegas, Nevada, 89106, United States
Yale University

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

ENDOMETRIAL ADENOCARCINOMA ENDOMETRIAL ADENOSQUAMOUS CARCINOMA ENDOMETRIAL CLEAR CELL ADENOCARCINOMA ENDOMETRIAL SEROUS ADENOCARCINOMA RECURRENT MALIGNANT UTERINE CORPUS NEOPLASM STAGE IIIA UTERINE CORPUS CARCINOMA OR CARCINOSARCOMA BY AJCC V7 STAGE STAGE IIIB UTERINE CORPUS CARCINOMA OR CARCINOSARCOMA BY AJCC V7 STAGE STAGE IIIC UTERINE CORPUS CARCINOMA OR CARCINOSARCOMA BY AJCC V7 STAGE STAGE IVA UTERINE CORPUS CARCINOMA OR CARCINOSARCOMA BY AJCC V7 STAGE STAGE IVB UTERINE CORPUS CARCINOMA OR CARCINOSARCOMA BY AJCC V7 STAGE