Hope for dravet families: phase 3 trial of zorevunersen launches

NCT ID NCT06872125

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 20 times

Summary

This study tests a new drug, zorevunersen, in 170 children aged 2 to 17 with Dravet syndrome, a severe form of epilepsy. The goal is to see if the drug can reduce seizure frequency and improve daily living skills compared to a sham procedure. Participants will be randomly assigned to receive either the drug or a placebo, and neither they nor their doctors will know which they receive.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advent Health Neuroscience Research Institute

    RECRUITING

    Orlando, Florida, 32804, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Arkansas Children's Hospital

    RECRUITING

    Little Rock, Arkansas, 72202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer

    RECRUITING

    Florence, Italy

    Contact

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CS Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact

  • Charité - Campus Virchow-Klinikum

    RECRUITING

    Berlin, Germany

    Contact

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Orange County

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Spain

    Contact

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, Italy

    Contact

  • Fukuoka Children's Hospital

    RECRUITING

    Fukuoka, Japan

    Contact

  • Great Ormond Street Hospital for Children

    RECRUITING

    London, WC1N 3JH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hokkaido University Hospital

    RECRUITING

    Hokkaido, Japan

    Contact

  • Hospital Blua Sanitas Valdebebas

    NOT_YET_RECRUITING

    Madrid, Spain

    Contact

  • Hospital Ruber Internacional

    RECRUITING

    Madrid, Spain

    Contact

  • Hôpital Necker - Enfants Malades

    RECRUITING

    Paris, France

    Contact

  • Hôpital Robert Debré - Paris

    RECRUITING

    Paris, France

    Contact

  • Hôpital de la Timone

    RECRUITING

    Marseille, France

    Contact

  • Integriertes Sozialpaediatrisches Zentrum

    RECRUITING

    München, Germany

    Contact

  • Istituto Giannina Gaslini-Ospedale Pediatrico IRCCS

    RECRUITING

    Genova, Italy

    Contact

  • Jichi Medical University Hospital

    RECRUITING

    Shimotsuke, Japan

    Contact

  • Kyoto University Hospital

    RECRUITING

    Kyoto, Japan

    Contact

  • LeBonheur Children's Hospital

    RECRUITING

    Memphis, Tennessee, 38103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NHO Shizuoka

    RECRUITING

    Shizuoka, Japan

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nagoya University Hospital

    RECRUITING

    Nagoya, Japan

    Contact

  • National Center of Neurology and Psychiatry

    RECRUITING

    Tokyo, Japan

    Contact

  • National Hospital Organization Nishi Niigata Central Hospital

    RECRUITING

    Niigata, Japan

    Contact

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nemours Children's Health

    RECRUITING

    Jacksonville, Florida, 32207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nicklaus Children's Hospital

    RECRUITING

    Miami, Florida, 33155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Okayama University Hospital

    RECRUITING

    Okayama, Japan

    Contact

  • Oregon Health & Science University (OHSU)

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Osaka City General Hospital

    RECRUITING

    Osaka, Japan

  • Ospedale Pediatrico Bambino Gesù

    RECRUITING

    Roma, Italy

    Contact

  • Phoenix Children's Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Hospital for Children

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sheffield Children's Hospital

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USCF Medical Center

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UVA Health

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaetsklinikum Bonn AoeR

    RECRUITING

    Bonn, Germany

    Contact

  • Universitaetsklinikum Frankfurt Goethe-Universitaet

    RECRUITING

    Frankfurt, Germany

    Contact

  • Universitaetsklinikum Freiburg

    RECRUITING

    Friedberg, Germany

    Contact

  • Universitaetsklinikum Heidelberg

    RECRUITING

    Heidelberg, Germany

    Contact

  • University of Iowa Hospital and Clinics

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Rochester Medical Center

    RECRUITING

    Rochester, New York, 14642, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Primary Children's Hospital

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact Phone: •••-•••-••••

  • Washington University in St. Louis School of Medicine

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10021, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yokohama City University Medical Center

    RECRUITING

    Yokohama, Japan

    Contact

Conditions

Explore the condition pages connected to this study.