Could a diabetes pill strengthen the right heart in lung hypertension?

NCT ID NCT06992440

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests whether empagliflozin, a diabetes medicine, can improve right heart function in 78 adults with pulmonary arterial hypertension (PAH). Participants continue their usual PAH treatments and receive either empagliflozin or a placebo. The main goal is to see if the drug increases the heart's pumping ability, measured by MRI.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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