New drug helps prevent bleeds in toddlers with hemophilia

NCT ID NCT05248594

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how the drug emicizumab (Hemlibra) works in real-world settings for infants and children up to 3 years old with hemophilia A, a bleeding disorder. Researchers tracked 71 children to see how many were using emicizumab to prevent bleeds and whether any breakthrough bleeding occurred. The goal was to understand how well the drug controls bleeding in very young patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

emicizumab (Hemlibra)

What this could lead to

If successful, this could show that emicizumab is a safe and effective option for preventing bleeds in very young children with hemophilia A.

What could go wrong

This is an observational study, not a controlled trial, so results may be less definitive. Breakthrough bleeding can still occur while on the drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital at Montefiore

    The Bronx, New York, 10467, United States

  • Comprehensive Center for Hemophilia and Coagulation Disorders (Cornell)

    New York, New York, 10065, United States

  • Connecticut Children's Hemophilia Treatment Center - Connecticut Children's Medical Center

    Hartford, Connecticut, 06106, United States

  • Dartmouth Hitchcock Hemophilia Center - Mary Hitchcock Memorial Hospital

    Lebanon, New Hampshire, 03766, United States

  • Mary M Gooley Hemophilia Center, Inc.

    Rochester, New York, 14621, United States

  • Newark Beth Israel

    Newark, New Jersey, 07112, United States

  • Northwell Health Hemostasis and Thrombosis Center

    Staten Island, New York, 11030, United States

  • SUNY Upstate Hemophilia Treatment Center - HTC 058

    Syracuse, New York, 13210, United States

  • Western NY Blood Care - Research Foundation for SUNY

    Buffalo, New York, 14202, United States

  • Yale Hemophilia Treatment Center

    New Haven, Connecticut, 06510, United States