Metformin's long shadow: does diabetes drug in pregnancy protect moms and kids years later?

NCT ID NCT06327191

Completed Knowledge-focused Sponsor: National University of Ireland, Galway, Ireland Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows up on 370 mothers and their children who were part of a larger trial testing metformin for gestational diabetes. Researchers want to see if taking metformin during pregnancy reduces the risk of diabetes, obesity, and heart problems in mothers up to 10 years later, and whether it affects children's weight. No new treatments are given; this is an observational follow-up to gather long-term health data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show whether metformin taken during pregnancy for gestational diabetes has lasting health benefits for mothers and children up to 10 years later.
What could go wrong: This is an observational follow-up, not a new treatment trial. Results may show no clear benefit or be limited by the original study's design and participant drop-out.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gestational diabetes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GESTATIONAL DIABETES

Contacts and locations

Locations

University Hospital Galway

Galway, Ireland

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Other studies related to the condition(s) this trial covers.