Metformin's long shadow: does diabetes drug in pregnancy protect moms and kids years later?

NCT ID NCT06327191

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows up on 370 mothers and their children who were part of a larger trial testing metformin for gestational diabetes. Researchers want to see if taking metformin during pregnancy reduces the risk of diabetes, obesity, and heart problems in mothers up to 10 years later, and whether it affects children's weight. No new treatments are given; this is an observational follow-up to gather long-term health data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show whether metformin taken during pregnancy for gestational diabetes has lasting health benefits for mothers and children up to 10 years later.

What could go wrong

This is an observational follow-up, not a new treatment trial. Results may show no clear benefit or be limited by the original study's design and participant drop-out.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gestational diabetes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Galway

    Galway, Ireland