Promising MDS combo trial halted early after only 3 patients

NCT ID NCT05918055

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tested two oral drugs, eltanexor and Inqovi, for people with high-risk myelodysplastic syndromes (MDS) whose disease did not improve with standard treatment. Only 3 adults enrolled before the trial was stopped. The goal was to find a safe dose and see if the combination could shrink cancer in the bone marrow. Because it was terminated early, we don't have clear results on how well it works.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.