New drug cocktail aims to keep relapsed myeloma in check

NCT ID NCT03030261

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II study tests whether a combination of elotuzumab, pomalidomide, and dexamethasone can help control relapsed multiple myeloma after a second stem cell transplant. The trial enrolls 25 adults whose myeloma returned after their first transplant. Participants receive the drug combo as maintenance therapy to delay further relapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

elotuzumab, pomalidomide, and dexamethasone

What this could lead to

If successful, this combination therapy could improve control of relapsed multiple myeloma and extend the time before the disease progresses again.

What could go wrong

This is a small, early-phase study with only 25 participants, so results may not apply to everyone. The drugs can cause side effects like low blood counts, infections, and fatigue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Colorado Blood Cancer Institute (Sarah Cannon)

    Denver, Colorado, 80218, United States

  • University Health Network - Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States