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Which works better: electric needle or foam injection for troubled leg veins?

NCT ID NCT04686097

Recruiting now Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial compares two minimally invasive procedures for treating incompetent perforating veins—veins that fail to close properly and can cause leg swelling, skin changes, or ulcers. One method uses a needle to deliver an electric current to seal the vein, while the other injects a sclerosing foam to close it. Researchers will measure which approach leads to better vein closure rates and improved quality of life over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
two procedures: ultrasound-guided puncture electrocoagulation and ultrasound-guided sclerosing agent injection
What this could lead to
If one method proves superior, it could become the preferred treatment for incompetent perforating veins, improving outcomes and quality of life.
What could go wrong
This is a relatively small trial with 84 participants, and results may not apply to all patients. Both procedures carry risks like pain, bruising, or incomplete vein closure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Varicose Ulcer venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCOMPETENT PERFORATING VEINS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Provincial Hospital

    SUSPENDED

    Hefei, Anhui, 230000, China

  • Sir Run Run Shaw Hospital

    SUSPENDED

    Hangzhou, Zhejiang, 310000, China

  • The second affiliated hospital of zhejiang university school of medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yantai Yuhuangding Hospital

    SUSPENDED

    Yantai, Shandong, 264000, China

  • Zhongshan Hospital affiliated to Fudan University

    SUSPENDED

    Shanghai, Shanghai Municipality, 200000, China