Can acupuncture needles calm the Body's Post-Surgery fire?

NCT ID NCT07795112

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 09, 2026 · Updated 4 times

Summary

Heart surgery with a heart-lung machine can trigger a strong inflammatory response that may harm organs and slow recovery. This trial tests whether electroacupuncture at the Zusanli (ST36) acupoint, a technique that sends mild electrical pulses through acupuncture needles, can reduce that inflammation. Researchers will enroll 140 adults undergoing elective cardiac surgery and randomly assign them to receive either electroacupuncture or a sham procedure with needles but no electricity, both alongside standard care. The study measures inflammation markers and organ function on the second day after surgery, along with recovery times, to see if this approach helps patients heal faster.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Electroacupuncture at bilateral Zusanli (ST36) acupoint
What this could lead to
If it works, this could offer a drug-free way to reduce inflammation and organ damage after heart surgery, potentially speeding recovery and shortening hospital stays.
What could go wrong
This is a single trial with 140 participants, and the effect of electroacupuncture on postoperative inflammation is still unproven. Results may not apply to all heart surgery patients, and the procedure carries minor risks like bleeding or discomfort at needle sites.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 140 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Scheduled to undergo elective cardiac surgery with cardiopulmonary bypass (CPB) support. * The surgical procedure may include coronary artery bypass grafting (CABG), valve replacement, valve repair, or another cardiac surgical procedure performed with CPB support. * Voluntarily agrees to participate in the study and provides written informed consent. If a participant is unable to read and sign the informed consent form because of incapacity or another reason, the informed consent process will be conducted with the participant's legally authorized representative, who will sign on the participant's behalf. If a participant is unable to read the informed consent form, the informed consent process will be witnessed by an independent witness, who will sign the informed consent form. Exclusion Criteria: * Membership in a vulnerable population other than older adults or individuals who are illiterate, including patients with psychiatric disorders, cognitive impairment, critical illness, or another vulnerable condition. * Pregnant or breastfeeding. * Local skin or soft-tissue infection, erysipelas, or another condition at the acupuncture site that makes acupuncture treatment unsuitable. * History of organ transplantation. * Active malignancy. * Long-term high-dose corticosteroid therapy before surgery, defined as prednisone ≥20 mg/day for ≥14 days or a cumulative prednisone-equivalent dose \>700 mg. * Severe chronic organ dysfunction before surgery, including any of the following: * Chronic respiratory disease with a baseline PaO₂/FiO₂ ratio \<300. * Hematological disease, such as leukemia, lymphoma, or myeloma, or a baseline platelet count \<100 × 10⁹/L. * Chronic liver disease with total bilirubin \>30 μmol/L. * History of stroke or cerebral hemorrhage with a baseline Glasgow Coma Scale score \<10. * Chronic renal insufficiency with serum creatinine \>110 μmol/L or long-term daily urine output \<500 mL. * Unable to tolerate electroacupuncture treatment. * Currently participating in another interventional clinical study. * Any other condition that, in the investigator's judgment, makes the patient unsuitable for participation.

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Conditions

The condition(s) this trial relates to.

Postoperative Complications Systemic Inflammatory Response Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

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