Can acupuncture needles calm the Body's Post-Surgery fire?
NCT ID NCT07795112
First seen Aug 31, 2026 · Last updated Sep 09, 2026 · Updated 4 times
Summary
Heart surgery with a heart-lung machine can trigger a strong inflammatory response that may harm organs and slow recovery. This trial tests whether electroacupuncture at the Zusanli (ST36) acupoint, a technique that sends mild electrical pulses through acupuncture needles, can reduce that inflammation. Researchers will enroll 140 adults undergoing elective cardiac surgery and randomly assign them to receive either electroacupuncture or a sham procedure with needles but no electricity, both alongside standard care. The study measures inflammation markers and organ function on the second day after surgery, along with recovery times, to see if this approach helps patients heal faster.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Electroacupuncture at bilateral Zusanli (ST36) acupoint
- What this could lead to
- If it works, this could offer a drug-free way to reduce inflammation and organ damage after heart surgery, potentially speeding recovery and shortening hospital stays.
- What could go wrong
- This is a single trial with 140 participants, and the effect of electroacupuncture on postoperative inflammation is still unproven. Results may not apply to all heart surgery patients, and the procedure carries minor risks like bleeding or discomfort at needle sites.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 140 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years. * Scheduled to undergo elective cardiac surgery with cardiopulmonary bypass (CPB) support. * The surgical procedure may include coronary artery bypass grafting (CABG), valve replacement, valve repair, or another cardiac surgical procedure performed with CPB support. * Voluntarily agrees to participate in the study and provides written informed consent. If a participant is unable to read and sign the informed consent form because of incapacity or another reason, the informed consent process will be conducted with the participant's legally authorized representative, who will sign on the participant's behalf. If a participant is unable to read the informed consent form, the informed consent process will be witnessed by an independent witness, who will sign the informed consent form. Exclusion Criteria: * Membership in a vulnerable population other than older adults or individuals who are illiterate, including patients with psychiatric disorders, cognitive impairment, critical illness, or another vulnerable condition. * Pregnant or breastfeeding. * Local skin or soft-tissue infection, erysipelas, or another condition at the acupuncture site that makes acupuncture treatment unsuitable. * History of organ transplantation. * Active malignancy. * Long-term high-dose corticosteroid therapy before surgery, defined as prednisone ≥20 mg/day for ≥14 days or a cumulative prednisone-equivalent dose \>700 mg. * Severe chronic organ dysfunction before surgery, including any of the following: * Chronic respiratory disease with a baseline PaO₂/FiO₂ ratio \<300. * Hematological disease, such as leukemia, lymphoma, or myeloma, or a baseline platelet count \<100 × 10⁹/L. * Chronic liver disease with total bilirubin \>30 μmol/L. * History of stroke or cerebral hemorrhage with a baseline Glasgow Coma Scale score \<10. * Chronic renal insufficiency with serum creatinine \>110 μmol/L or long-term daily urine output \<500 mL. * Unable to tolerate electroacupuncture treatment. * Currently participating in another interventional clinical study. * Any other condition that, in the investigator's judgment, makes the patient unsuitable for participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Eye ultrasound may spot brain swelling during aortic surgery
- Ultrasound could guide safer fluid dosing after heart surgery
- AI reads heart rhythms to predict surgery risks — could it replace unnecessary tests?
- A simple sensor on the back could warn of kidney danger during heart surgery
- A bedside score that could foretell heart surgery risks