Could a gentle zap to the scalp sharpen the Parkinson's brain?

NCT ID NCT05808504

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates whether a painless, low-intensity electrical current applied to the scalp can improve cognitive function — specifically the ability to stop an action when needed — in people with Parkinson's disease. The trial includes 50 Parkinson's patients and 40 healthy volunteers. Participants perform a computer task while brain activity is recorded, before and after real or sham stimulation, to see if the stimulation boosts inhibition and related brain networks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcranial alternating current electrical stimulation
What this could lead to
If it works, this could point toward a non-invasive, drug-free way to ease cognitive symptoms in Parkinson's disease.
What could go wrong
This is an early-stage study with a small number of participants. The stimulation may not improve cognition, and benefits might not last or apply to everyone.

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Conditions

The condition(s) this trial relates to.

Inhibition, Psychological Neurobehavioral Manifestations Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Rennes

    Rennes, France

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