New hope for rare liver disease as experimental drug enters Mid-Stage trial

NCT ID NCT05627362

Ongoing Disease control Sponsor: Ipsen Source: ClinicalTrials.gov ↗

Summary

This study is testing a drug called elafibranor in adults with primary sclerosing cholangitis (PSC), a rare disease that scars and blocks the liver's bile ducts. The main goal is to check the drug's safety and side effects. Researchers will also measure if it improves key liver blood tests and other markers of the disease over 12 weeks, comparing it to a placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Aberdeen Royal Infirmary NHS Grampian Grampian Health Board

Aberdeen, AB25 2ZD, United Kingdom
Ambrose King Centre-Royal London Hospital-Barts Health NHS Trust

London, E1 1BB, United Kingdom
American Research Corporation at The Texas Liver Institute

San Antonio, Texas, 78215, United States
Aspen Woods Clinic

Calgary, T3H 0V5, Canada
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

Palermo, 90127, Italy
Azienda Ospedaliera di Padova - U.O.C. di Gastroenterologia

Padua, 35128, Italy
Azienda Ospedaliero Universitaria Modena

Modena, 41124, Italy
Beth Israel Deaconess Medical Center, Liver Research Center

Boston, Massachusetts, 02215, United States
Bon Secours Richmond Community Hospital LLC. d/b/a Bon Secours Liver Institute of Richmond

Richmond, Virginia, 23226, United States
Brampton Civic Hospital (BCH) - Osler Hepatitis Centre

Brampton, Ontario, L6R 3J7, Canada
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Centre de Recherche du Centre Hospitalier de l'Universite de Montreal

Montreal, H2X 0A9, Canada
Centro Hospitalar Universitario Lisboa Norte

Lisbon, 1345-035, Portugal
Centro Hospitalar de Lisboa ocidental (CHLO), Hospital Egas Moniz

Lisbon, 1349-019, Portugal
Centro Hospitalar do Alto Ave - Hospital Senhora da Oliveira

Guimarães, 4800-055, Portugal
Charite Campus Virchow

Berlin, 13353, Germany
Covenant Research

Sarasota, Florida, 34240, United States
Frimley Park Hospital - Frimley Health NHS Foundation Trust

Frimley, GU16 7UJ, United Kingdom
G.I Research Institute

Vancouver, V6Z 2K5, Canada
Gastro Health Research

Cincinnati, Ohio, 45219, United States
Gastro One

Cordova, Tennessee, 38018, United States
Glasgow Royal Infirmary - Greater Glasgow Health Board

Glasgow, G4 0SF, United Kingdom
Gruppo Humanitas - Humanitas Research Hospital, Istituto Clinico Humanitas

Rozzano, 20089, Italy
Hospital De Montecelo

Pontevedra, 36071, Spain
Hospital General Universitario Gregorio Maranon (HGUGM)

Madrid, 28007, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Miguel Servet

Zaragoza, 50009, Spain
Hospital Universitario Puerta de Hierro

Majadahonda, 28222, Spain
Hospital Universitario Rio Hortega

Valladolid, 47012, Spain
Hospital Universitario Vall d'Hebron

Barcelona, 08035, Spain
Hull Royal Infirmary - Hull University Teaching Hospitals NHS Trust

Hull, HU3 2JZ, United Kingdom
Huron Gastroenterology Associates - Center for Digestive Care

Ypsilanti, Michigan, 48197, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Klinikum der Johann Wolfgang Goethe-Universitaet Frankfurt

Frankfurt, 60590, Germany
Liver Institute Northwest

Seattle, Washington, 98105, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Mercy Medical Center

Baltimore, Maryland, 21202, United States
New York University Langone Health

New York, New York, 06510, United States
Om Research LLC

Lancaster, California, 93534, United States
Ospedale Casa Sollievo della Sofferenza

San Giovanni Rotondo, 71013, Italy
Peak Gastroenterology Associates

Colorado Springs, Colorado, 80907, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Piedmont Hospital - Piedmont Transplant Institute

Atlanta, Georgia, 30309, United States
Queen Elizabeth Hospital

Birmingham, B15 2TT, United Kingdom
Rocky Mountain Gastroenterology (RMG)

Littleton, Colorado, 80120, United States
Schiff Center for Liver Diseases - University of Miami

Miami, Florida, 33136, United States
South Denver Gastroenterology,P.C.

Englewood, Colorado, 80113, United States
Southwest Gastroenterology Associates, PC (SWGA)

Albuquerque, New Mexico, 87109-4342, United States
Sutter Health Van Ness Campus Medical Office Building

San Francisco, California, 94109, United States
Tandem Clinical Research GI

Marrero, Louisiana, 70072, United States
The Royal Free Hospital - Royal Free London NHS Foundation Trust

London, NW3 2QG, United Kingdom
Thomas Jefferson University

Philadelphia, Pennsylvania, 19017, United States
Universitaetsklinikum Heidelberg - Nationales Centrum fuer Tumorerkrankungen

Heidelberg, 69120, Germany
University Hospital Ulm

Ulm, 89081, Germany
University Of Alberta Hospital-Zeidler Ledcor Centre

Edmonton, Alberta, T6G 2X8, Canada
University Of Texas Southwestern Medical Center At Dallas

Dallas, Texas, 75235, United States
University of Calgary

Calgary, Alberta, T2N 4Z6, Canada
University of California, Davis

Sacramento, California, 95817, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Virginia Medical Center

Charlottesville, Virginia, 22093, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States
Yale University School Of Medicine - Yale Center For Clinical Investigation

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

PRIMARY SCLEROSING CHOLANGITIS