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A surgical twist that could save ejaculation during prostate surgery

NCT ID NCT07777068

Disease control Sponsor: ALI KAMAL M. SAMI Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial tests whether a modified laser surgery for an enlarged prostate can relieve urinary blockage while preserving ejaculation. Men aged 50 and older with urinary symptoms are randomly assigned to either the standard laser vaporization or a version that leaves small tissue rims at the bladder neck and verumontanum. The main question is whether more men retain antegrade ejaculation three months after the modified surgery, while also comparing urinary symptom relief, flow rate, and complications over a year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ejaculation-preserving dual-wavelength diode laser vaporization of the prostate
What this could lead to
If successful, this technique could offer men with enlarged prostate a surgery option that relieves urinary symptoms while preserving ejaculation, improving quality of life.
What could go wrong
The trial is relatively small and early, and preserving ejaculation might come at the cost of less effective urinary symptom relief. Complications and individual variation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

119 people

The number who actually took part.

Started

Oct 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male, aged 50 years or older * Lower urinary tract symptoms attributable to benign prostatic obstruction * International Prostate Symptom Score of 16 or more * Maximum urinary flow rate below 15 mL/s on a uroflowmetry study with a voided volume of at least 150 mL * Prostate volume between 30 and 150 cc on transabdominal ultrasound * Indication for surgery after failure of or intolerance to medical therapy * Preserved antegrade ejaculation at baseline * Currently sexually active * Willing and able to attend all scheduled follow-up visits * Written informed consent, including specific consent to discussion and recording of ejaculatory function Exclusion Criteria: * Suspected or confirmed prostate cancer * Prostate-specific antigen above the age-specific reference range without a benign explanation * Neurogenic bladder * Urethral stricture * Bladder stones * Previous prostatic or urethral surgery * Absent antegrade ejaculation at baseline * Erectile dysfunction sufficient to preclude sexual activity

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia bladder neck obstruction Retrograde Ejaculation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign prostatic hyperplasia Bladder outlet obstruction Lower urinary track symptoms

Contacts and locations

Locations

  • Royal Hospital, Department of Urology

    Sulaymaniyah, Kurdistan, 46001, Iraq

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