A simple swallow exercise might ease a hidden Parkinson's danger
NCT ID NCT07773025
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This trial tests whether a 4-week effortful swallow exercise program can improve swallowing in adults with Parkinson's disease who have trouble swallowing. Participants are split into two groups: one starts the exercise right away, the other waits 4 weeks before starting. Swallowing is measured with video X-rays and questionnaires, with follow-up at 6 and 12 months. The goal is to see if this simple home-based exercise can make swallowing safer and reduce risks like choking.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Effortful swallow exercise program
- What this could lead to
- If effective, this simple home-based exercise could offer a non-drug way to improve swallowing safety and reduce choking risk in Parkinson's disease.
- What could go wrong
- The trial is relatively small and early-stage, and results may not apply to all people with Parkinson's. The exercise requires consistent practice and may not help everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 74 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Neurologist-confirmed diagnosis of Parkinson disease * Self-report of one or more swallowing symptoms, such as difficulty managing secretions, coughing during meals, choking on food, or respiratory infection other than COVID-19 in the past 6 months * Baseline videofluoroscopic swallowing assessment showing prolonged time to laryngeal vestibule closure and/or poor pharyngeal area at maximum constriction on regular-effort swallows with thin or mildly thick liquid stimuli, relative to healthy reference values Exclusion Criteria: * History of head and neck cancer * History of radical neck dissection, anterior cervical spine surgery, or neck/oropharyngeal surgery, except tonsillectomy or adenoidectomy * History of any neurological disease other than Parkinson disease * Cognitive or receptive communication difficulties that preclude the ability to follow English-language study instructions * History of brain surgery, including deep brain stimulation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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