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Brain waves may reveal which children recover from encephalopathy

NCT ID NCT07825675

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

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Registered, but not yet taking participants.
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Cancelled before anyone took part.

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First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers at Assiut University Children Hospital are studying whether abnormal brain-wave patterns on an EEG can predict how well children with encephalopathy recover. The study follows 147 children aged 1 month to 18 years who have altered consciousness from encephalopathy. Each child receives an EEG within 48 hours of hospital admission, and researchers track neurological outcomes at discharge using a standard pediatric scale. The goal is to learn whether specific EEG features, such as background slowing or seizures, signal a higher risk of poor recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If early EEG patterns reliably flag which children will struggle, doctors could spot high-risk cases sooner and direct care and family counseling more precisely.
What could go wrong
This is an observational study at a single hospital, so it cannot prove that EEG changes cause poor outcomes. The findings may not hold for children with different causes of encephalopathy or in other hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 147 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children aged 1 month to 18 years admitted with encephalopathy to the Pediatric Intensive Care Unit, Pediatric Neurology Unit, or Emergency Unit of Assiut University Children Hospital.

Ages

1 month to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 1 month to 18 years * Clinical diagnosis of encephalopathy with altered level of consciousness * EEG performed within the first 48 hours of admission * Written informed consent from parents or legal guardians Exclusion Criteria: * Neonatal encephalopathy * Children with severe pre-existing neurological disability * Known epileptic patients * Incomplete clinical or EEG data

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Conditions

The condition(s) this trial relates to.

brain disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain diseases Encephalopathy

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

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