EEG clues may reveal who benefits from seizure drug

NCT ID NCT07555171

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at whether specific brain wave patterns on an EEG can predict how well the drug fenfluramine works for people with Lennox-Gastaut Syndrome (LGS), a severe form of epilepsy. Researchers will follow 20 children and adults aged 2 to 35 who are already taking fenfluramine. The goal is to find EEG markers that show if the drug is helping, giving doctors a better way to tailor treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fenfluramine

What this could lead to

If successful, this could help doctors predict which LGS patients will benefit most from fenfluramine, personalizing treatment.

What could go wrong

This is a small, early-stage observational study with only 20 participants, so results may not apply broadly. It focuses on markers, not a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Lennox-Gastaut syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States