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ECMO in kids with cancer: a closer look at survival and risks

NCT ID NCT07712835

Knowledge-focused Sponsor: Children's Mercy Hospital Kansas City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study examines how children under 18 with cancer or a history of a stem cell transplant do when they need a machine called ECMO to help them breathe. Researchers looked at bleeding, infections, and survival rates in children treated at one hospital, and compared survival with similar children who did not receive ECMO at another hospital. The goal is to better understand the risks and benefits of ECMO in this fragile group of patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
extracorporeal membrane oxygenation (ECMO)
What this could lead to
If successful, this study could help doctors better understand when ECMO might help children with cancer or a stem cell transplant who have severe breathing failure.
What could go wrong
This is a small, observational study, not a controlled trial. It cannot prove that ECMO improves outcomes, only describe what happened in these specific hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

22 people

The number who actually took part.

Started

Feb 2015

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pediatric patients, under the age of 18, admitted to a tertiary care pediatric intensive care unit for management of respiratory failure warranting mechanical ventilation. Beyond this, only pediatric patients with an underlying oncologic and/or hematopoietic stem cell transplant were included in the study.

Ages

4 weeks to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Less than 18 years old * Admitted to the PICU for respiratory failure (2015-2023) * Underlying oncologic diagnosis and/or hematopoietic stem cell transplant * Mechanical ventilation

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Conditions

The condition(s) this trial relates to.

cancer hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm neoplasm respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ecmo outcomes Hematopoetic stem cell transplant Malignancies, hematologic Respiratory failure (pediatric patients) Solid tumor malignancies

More trials for these conditions

Other studies related to the condition(s) this trial covers.