ECMO studied in 761 severe COVID-19 patients: does it help?

NCT ID NCT04397588

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether ECMO, a machine that does the work of the heart and lungs, helps people with severe COVID-19 who have lung failure or heart failure. Researchers tracked 761 patients across France to see how many survived and how quickly they recovered. The goal was to understand if ECMO is a useful option for the sickest COVID-19 patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Extracorporeal membrane oxygenation (ECMO)

What this could lead to

If successful, this could clarify whether ECMO improves survival in the sickest COVID-19 patients, guiding future treatment protocols.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove ECMO is better than other treatments. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 heart failure myocarditis severe acute respiratory syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM la Timone- Marseille University Hospital

    Marseille, 13005, France

  • APHP Bichat - Paris University Hospital

    Paris, 75018, France

  • APHP Henri Mondor Paris University Hospital

    Créteil, 94000, France

  • APHP Hopital Européen Georges Pompidou - Paris University Hospital

    Paris, 75015, France

  • APHP Kremli Bicetre Paris University Hospital

    Le Kremlin-Bicêtre, 94275, France

  • APHP La Pitié Salpêtrière Paris University Hospital

    Paris, 75651, France

  • APHP necker Paris University Hospital

    Paris, 75015, France

  • Ambroise Paré Hospital

    Neuilly-sur-Seine, 92200, France

  • Angers University Hospital

    Angers, 49933, France

  • Besançon Hospital

    Besançon, 25030, France

  • Bordeaux University Hospital

    Pessac, 33604, France

  • Brest university Hospital

    Brest, 29200, France

  • Bretagne Atlantique Hospital

    Vannes, 56000, France

  • Caen University Hospital

    Caen, 14033, France

  • Clairval Hospital

    Marseille, 13009, France

  • Clermont ferrand University hospital

    Clermont-Ferrand, 63003, France

  • Clinique de la Sauvegarde

    Lyon, 69337, France

  • Dijon University Hospital

    Dijon, 21079, France

  • Emile Muller Hospital

    Mulhouse, 68051, France

  • Grenoble University Hospital

    La Tronche, 38700, France

  • Institut Mutualiste Montsouris

    Paris, 75014, France

  • La Réunion University Hospital

    Saint-Denis, 97400, France

  • Lens Hospital

    Lens, 62307, France

  • Lille University Hospital

    Lille, 59000, France

  • Limoges University Hospital

    Limoges, 87042, France

  • Lyon University Hospital

    Lyon, 69500, France

  • Marie Lannelongue Hospital

    Le Plessis-Robinson, 92350, France

  • Marseille Européen Hospital

    Marseille, 13003, France

  • Metz University Hospital

    Metz, 45000, France

  • Montpellier University Hospital

    Montpellier, 34090, France

  • Nancy University Hospital

    Nancy, 54511, France

  • Nantes University Hospital

    Nantes, 44000, France

  • Nimes University Hospital

    Nîmes, 30029, France

  • Poitiers University hospital

    Poitiers, 86000, France

  • Reims University hospital

    Reims, 51092, France

  • Rennes University hospital

    Rennes, 35000, France

  • Rouen University Hospital

    Rouen, 76031, France

  • Saint Etienne University Hospital

    Saint-Etienne, 42000, France

  • Saint Nazaire Hospital

    Saint-Nazaire, 44606, France

  • Saint brieuc Hospital

    Saint-Brieuc, 22027, France

  • Strasbourg University Hospital

    Strasbourg, 67091, France

  • Toulouse University Hospital - Rangueil Hospital

    Toulouse, 31000, France

  • Tours University Hospital

    Tours, 37044, France

  • Vendée Hospital

    La Roche-sur-Yon, 85000, France