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New exercise approach may boost heart function in heart failure patients

NCT ID NCT06032780

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if eccentric resistance training (a type of exercise that focuses on lengthening muscles) can improve heart function and exercise ability in people with chronic heart failure. About 84 adults with stable heart failure will be assigned to either eccentric training or standard aerobic and resistance training for 12 weeks. The goal is to see which approach better helps the heart pump and improves how far patients can walk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of Chronic HF and currently stable with optimal medical therapy * Chronic Heart failure with ejection fraction \> 30 % * Patient able to safely perform lower limb exercise will be check by six- minute walk test (6 MWT) Exclusion Criteria: * Those Heart failure patient whose are in acute phase or planed for any immediate medical intervention * Already participating in cardiac rehabilitation * New York Heart Association (NYHA) Classification of HF class IV HF symptoms * Co-existent other disease such as asthma/ COPD/interstitial lung disease. * Symptomatic Second degree or third degree heart block. * ECG with uncontrolled ventricular arrhythmia * Limited Exercise ability due to neurologic or orthopedic impairments of the legs (will cross-check with 6 MWT)

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Pakistan Railway Hospital

    SUSPENDED

    Rawalpindi, Punjab Province, 46000, Pakistan

  • Rawalpindi Institute of Cardiology

    RECRUITING

    Rawalpindi, Punjab Province, 46000, Pakistan

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