Could adding vasopressin early save more lives in sepsis shock?

NCT ID NCT06464510

First seen Feb 01, 2026 · Last updated May 12, 2026 · Updated 16 times

Summary

This study compares two ways of treating dangerously low blood pressure in people with sepsis. One group gets the standard drug norepinephrine plus early vasopressin, while the other gets vasopressin only if needed as a rescue. The goal is to see if early use of vasopressin reduces death or the need for kidney dialysis within 28 days. About 2,800 adults in intensive care will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BP-A Beneficiência Portuguesa de São Paulo

    NOT_YET_RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Email: •••••@•••••

  • Hospital Alemão Oswaldo Cruz

    NOT_YET_RECRUITING

    São Paulo, São Paulo, Brazil

    Contact

  • Hospital Geral de Caxias do Sul

    RECRUITING

    Caxias do Sul, Rio Grande do Sul, Brazil

    Contact

  • Hospital Nereu Ramos

    RECRUITING

    Florianópolis, Santa Catarina, Brazil

    Contact Email: •••••@•••••

  • Hospital SEPACO

    NOT_YET_RECRUITING

    São Paulo, S, Brazil

    Contact

  • Hospital São Paulo - UNIFESP

    RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Email: •••••@•••••

  • Hospital de Amor - Unidade Barretos (Fundação PIO XII)

    NOT_YET_RECRUITING

    Barretos, São Paulo, Brazil

    Contact

  • Hospital do Coracao

    RECRUITING

    São Paulo, São Paulo, 05435000, Brazil

    Contact

    Contact

Conditions

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