New approach aims to tame immune storms in Half-Matched transplants

NCT ID NCT06828796

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 31 times

Summary

This study tests whether giving the immune-suppressing drug tacrolimus earlier than usual can lower the risk of cytokine release syndrome (CRS), a severe inflammatory reaction, in patients receiving a half-matched stem cell transplant for blood cancer. About 20 adults will receive the modified drug schedule. The goal is to make the transplant safer while still controlling the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northside Hospital

    RECRUITING

    Atlanta, Georgia, 30342, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

disease hematologic disorder hematopoietic and lymphoid cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.