Early liver transplant offers hope for severe alcoholic hepatitis patients

NCT ID NCT01756794

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether early liver transplantation can help people with severe alcoholic hepatitis who did not get better with medical treatment. Researchers compared alcohol relapse rates in 284 patients who received early transplants to those transplanted after a 6-month sobriety period. The goal was to see if early transplantation is a safe and effective option for carefully selected patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liver transplantation

What this could lead to

If successful, this could confirm that early liver transplantation is a viable option for carefully selected patients with severe alcoholic hepatitis, potentially saving lives.

What could go wrong

This is a completed study, but results may not apply to all patients. Alcohol relapse remains a risk, and the selection process is very strict, limiting who can benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcoholic hepatitis alcoholic liver cirrhosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study site

    Ghent, Belgium

  • Hospital Antoine Béclère (Assistance Publique des Hôpiaux de Paris)

    Clamart, 92141, France

  • Hospital Sart Tilman

    Liège, Belgium

  • Hôpital Beaujon (AH-HP)

    Clichy, 92118, France

  • Hôpital Cochin (AH-HP)

    Paris, 75014, France

  • Hôpital Henri Mondor (AP-HP)

    Créteil, 94000, France

  • Hôpital Jean Verdier (AH-HP)

    Bondy, 93143, France

  • Hôpital Paul Brousse (AH-HP)

    Villejuif, 94000, France

  • Hôpital Saint Antoine (AP-HP)

    Paris, 75012, France

  • Hôpital de la Pitié-Salpétrière (AP-HP)

    Paris, 75013, France

  • ULB, Erasme

    Brussels, 1070, Belgium

  • UZA

    Antwerp, Edegem, B-2650, Belgium

  • University Hospital

    Montpellier, 34295, France

  • University Hospital

    Pessac, 33604, France

  • University Hospital

    Strasbourg, 67100, France

  • University hospital

    Angers, 49933, France

  • University hospital

    Besançon, 25030, France

  • University hospital

    Brest, 29609, France

  • University hospital

    Caen, 14000, France

  • University hospital

    Dijon, 21079, France

  • University hospital

    Grenoble, 38043, France

  • University hospital

    Lille, 59037, France

  • University hospital

    Lyon, 69437, France

  • University hospital

    Nancy, 54500, France

  • University hospital

    Nantes, 44035, France

  • University hospital

    Nice, 06202, France

  • University hospital

    Poitiers, 86021, France

  • University hospital

    Reims, 51092, France

  • University hospital

    Rennes, 35033, France

  • University hospital

    Toulouse, 31059, France

  • Univesity hospital

    Amiens, 80054, France

  • Univesity hospital

    Chambray-lès-Tours, 37170, France