Early liver transplant offers hope for severe alcoholic hepatitis patients
NCT ID NCT01756794
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether early liver transplantation can help people with severe alcoholic hepatitis who did not get better with medical treatment. Researchers compared alcohol relapse rates in 284 patients who received early transplants to those transplanted after a 6-month sobriety period. The goal was to see if early transplantation is a safe and effective option for carefully selected patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- liver transplantation
- What this could lead to
- If successful, this could confirm that early liver transplantation is a viable option for carefully selected patients with severe alcoholic hepatitis, potentially saving lives.
- What could go wrong
- This is a completed study, but results may not apply to all patients. Alcohol relapse remains a risk, and the selection process is very strict, limiting who can benefit.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Study site
Ghent, Belgium
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Hospital Antoine Béclère (Assistance Publique des Hôpiaux de Paris)
Clamart, 92141, France
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Hospital Sart Tilman
Liège, Belgium
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Hôpital Beaujon (AH-HP)
Clichy, 92118, France
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Hôpital Cochin (AH-HP)
Paris, 75014, France
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Hôpital Henri Mondor (AP-HP)
Créteil, 94000, France
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Hôpital Jean Verdier (AH-HP)
Bondy, 93143, France
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Hôpital Paul Brousse (AH-HP)
Villejuif, 94000, France
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Hôpital Saint Antoine (AP-HP)
Paris, 75012, France
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Hôpital de la Pitié-Salpétrière (AP-HP)
Paris, 75013, France
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ULB, Erasme
Brussels, 1070, Belgium
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UZA
Antwerp, Edegem, B-2650, Belgium
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University Hospital
Montpellier, 34295, France
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University Hospital
Pessac, 33604, France
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University Hospital
Strasbourg, 67100, France
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University hospital
Angers, 49933, France
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University hospital
Besançon, 25030, France
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University hospital
Brest, 29609, France
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University hospital
Caen, 14000, France
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University hospital
Dijon, 21079, France
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University hospital
Grenoble, 38043, France
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University hospital
Lille, 59037, France
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University hospital
Lyon, 69437, France
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University hospital
Nancy, 54500, France
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University hospital
Nantes, 44035, France
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University hospital
Nice, 06202, France
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University hospital
Poitiers, 86021, France
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University hospital
Reims, 51092, France
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University hospital
Rennes, 35033, France
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University hospital
Toulouse, 31059, France
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Univesity hospital
Amiens, 80054, France
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Univesity hospital
Chambray-lès-Tours, 37170, France
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