Blood test and imaging aim to spot nerve damage before symptoms worsen
NCT ID NCT05311488
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared different ways to detect early nerve damage in people with hereditary TTR amyloidosis, a condition that can cause progressive nerve problems. Researchers used blood tests, skin imaging, and standard nerve exams in 47 participants. The goal was to see which tools work best for catching nerve damage early, which could help start treatment sooner.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to earlier diagnosis of nerve damage in people with hereditary TTR amyloidosis, allowing for earlier treatment.
- What could go wrong
- This is a small, completed study focused on comparing diagnostic tools, not testing a treatment. The results may not apply to all patients or lead to immediate changes in care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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