New study tracks nerve damage marker in rare genetic disease

NCT ID NCT06360289

First seen Nov 17, 2025 · Last updated May 08, 2026 · Updated 19 times

Summary

This study looks at a protein called NfL in the blood of people who carry a TTR gene variant, both those without symptoms and those with hATTR amyloidosis affecting nerves. The goal is to see if NfL levels can help detect when the disease starts, how it progresses, and how well treatments work. About 500 participants will be followed over time at a single center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Universitaire (CHU) Le Kremlin-Bicêtre Assistance Publique-Hôpitaux de Paris (APHP)

    RECRUITING

    Paris, Île-de-France Region, 94270, France

Conditions

Explore the condition pages connected to this study.