Can Botox-Like shots straighten Teens' spines?
NCT ID NCT03935295
First seen Jun 25, 2026 · Last updated Jun 25, 2026
Summary
This study tests whether injecting Dysport (a muscle relaxant similar to Botox) into back muscles, combined with wearing a brace, can improve spine curvature in teens aged 10-16 with mild to moderate scoliosis. About 90 participants will receive either Dysport or a placebo, plus a custom brace. The main goal is to see if the curve angle changes over time.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
abobotulinumtoxinA (Dysport)
What this could lead to
If it works, this could offer a non-surgical way to slow or reduce spine curvature in teens with scoliosis, potentially avoiding the need for surgery.
What could go wrong
This is a small Phase 4 study with only 90 participants. The treatment may not improve curve progression more than bracing alone, and injections carry risks like muscle weakness or pain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.